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MASON, Ohio -- Andy Murray followed up his second Olympic singles title with a second-round victory on Wednesday night in the Western & Southern Open.The top-seeded Scot beat Argentinas Juan Monaco 6-3, 6-2 to set up a match against South Africas Kevin Anderson, a 6-2, 6-4 winner over 13th-seeded Richard Gasquet of France.Murray had trouble adjusting to the balls and called for a trainer to attend to his right shoulder in the first set. He won nine of the final 11 games.Theres different balls here, and thats something thats not easy for a tennis player, and you have to be careful with that, Murray said. It totally changes how it feels on the racket and how it feels through your body, as well. I served better in the second set. Its just at the start, it was a bit sore. Ive played a lot of tennis, but its also the ball change.On Sunday in Rio, Murray beat Argentinas Juan Martin del Potro in four sets in the final.Murray won the hard-court event in 2008 and 2011 and has reached the quarterfinals in eight of his previous 11 appearances in Cincinnati.Earlier, Rafael Nadal defeated Uruguays Pablo Cuevas 6-1, 7-6 (4).Nadal, the third-seeded Spanish star who won the tournament in 2013, also was coming off the Olympics, where he teamed with Marc Lopez to win the doubles title and lost in the bronze-medal singles match. Before that, the 30-year-old Nadal had missed two months with an injured left wrist.I think I played well, Nadal said. I think I played a good match against a tough opponent in the first round for me for sure. After coming from Rio and after the marathon that I had, its a very important victory for me. So Im very happy.Nadal avenged a loss to Cuevas in February in Rio de Janeiro in a clay-court event to set up a third-round match against Croatias Borna Coric, a 7-6 (2), 4-6, 7-6 (6) winner over 14th-seeded Nick Kyrgios of Australia.Second-seeded Stan Wawrinka of Switzerland also advanced, beating American Jared Donaldson 2-6, 6-3, 6-4.Also, fourth-seeded Milos Raonic of Canada outlasted American John Isner 7-6 (5), 7-6 (5); fifth-seeded Kei Nishikori?of Japan topped Russias Mikhail Youzhny 6-3, 6-2; sixth-seeded Tomas Berdych of the Czech Republic beat Spains Marcel Granollers 6-3, 7-6 (4); and seventh-seeded Jo-Wilfried Tsonga of France edged American Reilly Opelka 7-6 (5), 7-6 (3).Defending champion Roger Federer and top-ranked Novak Djokovic are sidelined by injuries.In womens second-round play, second-seeded Angelique Kerber of Germany beat Frances Kristina Mladenovic 6-0, 7-5; third-seeded Simona Halep of Romania edged Germanys Annika Beck 6-3, 6-1; and fourth-seeded Garbine Muguruza of Spain topped American Coco Vandeweghe 7-6 (4), 6-2.With two-time defending champion Serena Williams forced to withdraw because of an inflamed shoulder, Kerber is in position to take the top spot in the rankings with a tournament victory. Williams has been in the top spot for 183 consecutive weeks.Its not on my mind, Kerber said. If the time is ready and I can reach the No. 1, of course,it will be amazing. Still, its for me still a long, long way to get there.Halep has won 11 straight matches and her last two tournaments at Bucharest and Montreal.I feel confident. I had pretty good tournaments before coming here, and I feel my game, Halep said. I was a little bit nervous before the match, because I had two weeks after without matches. Like everyone says, its tough, the first match of the tournament. Now Im more relaxed and Im looking already forward to the next one.Rain delayed the start of play for 90 minutes. The tournament had 39 singles matches scheduled for Wednesday, making up for weather delays over the first two full days of play. There were eight matches either suspended or postponed from Tuesday that were completed on Wednesday. All eight winners played second matches in the evening. 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Garnett was dealt -- along with Paul Pierce -- to Brooklyn during the off-season. CHESTNUT HILL, Mass. -- Louisville quarterback Lamar Jackson added more highlights to his Heisman Trophy resume against Boston College on Saturday, scoring seven total touchdowns in a 52-7 win.Jackson has 45 total touchdowns this season, on pace to break the FBS record Colt Brennan set in Hawaii in 2006 (63 in 14 games). He also became the first Louisville quarterback to pass 1,000 yards rushing.It was not all smooth sailing for the Heisman front-runner. Jackson missed two drives in the second quarter because a cramp in his arm made his fingers go numb temporarily. He went into the locker room at halftime and got an IV, then returned to score two more touchdowns in the second half.It was kind of getting tight, Jackson said. I was like, Man, I cant do this. I cant throw.Jackson said it was the first time he had cramping in his arm. He was asked whether hee had any lingering effects after the treatment at halftime.ddddddddddddNo, Im good. 100 percent, he said.Jackson had two runs that went 50 or more yards: a 69-yarder to open the game, and a 53-yarder to end his day. He ended up with 416 yards of total offense, giving him 3,934 on the season. Next week against Wake Forest, Jackson needs 115 yards to break the single-season school record of 4,048 set by Teddy Bridgewater in 2013.Hes played some really good games, and I think what we see in practice is how well hes reading and how much hes really focusing on seeing the coverages and the movement of the defense, so his decision-making has really gotten better, and he works and pushes himself in practice, coach Bobby Petrino said. ' ' '